From BLOOD:
1. Stereotyped patterns of somatic hypermutation in subsets of patients with chronic lymphocytic leukemia: implications for the role of antigen selection in leukemogenesis
2. Comprehensive characterization of IGHV3-21–expressing B-cell chronic lymphocytic leukemia: an Italian multicenter study
3. Constitutive activation of distinct BCR-signaling pathways in a subset of CLL patients: a molecular signature of anergy
4. Over 20% of patients with chronic lymphocytic leukemia carry stereotyped receptors: pathogenetic implications and clinical correlations
From other journals:
5. Ig VH1 genes expressed in B cell chronic lymphocytic leukemia exhibit distinctive molecular features
6. Evidence of biased immunoglobulin variable gene usage in highly stable B-cell chronic lymphocytic leukemia
7. High frequency of p53 dysfunction and low level of VH mutation in chronic lymphocytic leukemia patients using the VH3–21 gene segment
8. Routine analysis of IgVH mutational status in CLL patients using BIOMED-2 standardized primers and protocols
9. Signature of B-CLL with different prognosis by Shrunken centroids of surface antigen expression profiling
10. ZAP-70 compared with immunoglobulin heavy-chain gene mutation status as a predictor of disease progression
in chronic lymphocytic leukemia.
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Do you think you are a clever boy or girl? If you are clever, which ways do you choose to succeed? In all your choices do you choose diligence? A failing man may say “yes “or “no”. But a successful man must say “yes”. Because they believe “diligent will not definitely succeed but not industrious will definitely fail.
In my middle school, I met a boy who was very clever but never study. He was always because of playing computer games and forgot to finish his homework. He was always because of talking about the games in the class and was criticized by teacher. He was always because of going to school later and was punished to stand the last row. To my surprise, every exam he always got a good achievement. However, I was always working hard but often failed exam. At the beginning, I wanted to give up but suddenly a sentence appeared in my mind ,”Genius is one percent inspiration and nine percent perspiration” So I believed “I shall definitely succeed” As time went by, an important exam would around corner which decide us to which high middle school. I was still working hard even working harder, but he was still depending on his cleverness. In the end, I went to an ideal high school, but he failed the exam.
Although I am not a clever girl, I am a diligent girl. A diligent girl gets the success.
In my high school, I heard the clever boy begin to study. He was always because of studying and forgot to have lunch. He was always because of wanting to finish the homework and gave up the playing time. He was always because of solving a difficult question and done many times. Finally, he succeeds. He went to an ideal university.
There is a sentence “Genius nothing but labor and diligence “, so I more firmly believe “Although you are very clever, you also need diligence” If you want to be a successful man.
When you meet difficult, don’t give up and insist. Believe a sentence “A diligent girl can win “. Good luck to you!
It’s been two years since I gratuated from school.I ofen recalled the memory when I studied at school.The most I can remember are the subjects that school arranged for us.But the knowledge we acquired is hardly useful.I wish I had acquired more useful knowledge so that I can better adapt myself to the society.China’s education stresses textbook knowledge rather than a fundamental understanding of subjects.Both teachers and parents look at education with an eye on fame and success.For them,a successful education means entering a pretigious school or getting high grades in tests,while neglecting the fact that education also plays a crucial role in nurturing a healthy and a complete personality.I remembered the time when I’m in high school,I have to burn the midnight oil to deal with my homework.Though it’s a good memory now.Many students are still doing so.And I think many parents pressure their children too much by sending them to various after-school classes.They pay too much attention on students’ academic merit,so there will be a long way for China to deliver a good education to all children.
When times become difficult (and you know they sometimes will), remember a moment in your life that was filled with joy and happiness. Remember how it made you feel, and you will have the strength you need to get through any trial.
I don’t like my life right now. I don’t like my life style either. Today I just nissed the really important exam. I feel so bad about it. It’s the kind of final exam and few credits is related on it.
Anyway, I don’t like everything about myself. Oh, God…
“Life is like a box of chocolates, you’ll never know what you’re gonna get.”
It is the most distinguished actor’s line from the movie Forrest Dump, which has actually become most people’s motto of life.
Finished watching this movie at wee hours today, I felt a pity that I hadn’t seen it earlier. It has been known to everyone that it has become the most classical since it was a hit in is time, and I have absolutely long planned to enjoy it. Years passed by but I would always have no time for this kind of pure appreciation until midnight yesterday, when I finally made my mind.
Since entering my college, I have got more chances to enjoy different kinds of movies, and beyond peradventure it has become one of my hobbies.
What’s so amazing about life is its unpredictability, you’re never gonna guess what’s going to happen tomorrow, but do believe that hope is always around the corner…As to the protagonist, Forrest Gump, the mentally-challenged but promising guy, life always seems to produce miracles. Born with low IQ, he’s always dispised by his peers, but his mother, a wise forward-looking woman who insists on his going to public school as other nomal children do, always makes her beloved little son believe that he is no different from any other children.
Handicapped but lucky, Forrest has met his woman in life and made his fortune. He has had a narrow escape during the war in Vietnam and been honored the highest award in army. He’s also talented for running, military skills and table tennis. So you see, god always gets one door closes, and two others open.
A moron as he is, Forrest Gump achieved far more success than what the normal people could ever imagine. His achievement can be attributed to luck, integrity and the most important of all, the spirit of never giving up.
It’s true that I have udergone lots of depression these days, and I can hardly think about it optimistically. After watching Forrest Gump, I have somehow felt some strength from the hero in the movie. I am not stupid enough to think that the legend of Forrest Gump in the movie is gonna resurrect in reality. Movies are movies, which are exquisitely shot to condition our naive mind and somewhat exaggerated, but I firmly believe that what they are to convey us is the true meaning of life. So be true to yourself, that is the basic core.
The past has passed, however tough the road of life forward is, I’m gonna stick it out. Miracle is a shooting star, which will strike on you when you least expect it. I never expect to meet with prosperious success, but I do sincerely hope that life’s gonna change a little bit with my hardwork every day, baby step maybe…
The very sentence frequently welling up from my mind is the short line from Dead Poet Socity — SEIZE THE DAY. And from Forrest I have seized the main idea of being optimistic about adversity, and never succumbing…